1. Do you need a structured central repository of information?

2. Is more than one entity reading or writing transactions to a database?

3. Is there less than total trust between parties/entities in the ecosystem (for example, one user will not accept the "truth" as reported by another user)?

4. Are central gatekeepers introducing costs and /or "friction" when verifying transactions (for example, manual verification)?

5. Are there routine or logical interactions that occur that could be programmed to self-execute (for example, smart contracts)?